University of Oxford
McCullagh Research Group
Chemistry Research Laboratory, University of Oxford
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IC-MS

Ion-chromatography coupled to mass spectrometry (IC-MS)

IC-MS can be used to separate, identify and quantify a very wide range of ionisable compounds in complex samples, including those from inorganic, organic, environmental and biological origins, and is currently being applied in areas including environmental studies, forensics, medicinal chemistry, cell biology and metabolomics. IC-MS is the last of the main chromatographic types to be coupled directly with mass spectrometry, enabling exciting applications and new research capabilities, especially for life-science, environmental, and medical sciences. We have developed this technique for metabolomics application and demonstrated its capabilities for cell, tissue and bio-fluid applications (Walsby-Tickle et al., Communications Biology, 2020)

IC-MS separation space (indicative)

james
Selected publications
eje 21 0850 page
idh resistance page